4-Phenylbutyrate Inhibits Tunicamycin-Induced Acute Kidney Injury via CHOP/GADD153 Repression

Different forms of acute kidney injury (AKI) have been associated with endoplasmic reticulum (ER) stress; these include AKI caused by acetaminophen, antibiotics, cisplatin, and radiocontrast. Tunicamycin (TM) is a nucleoside antibiotic known to induce ER stress and is a commonly used inducer of AKI....

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Detalles Bibliográficos
Autores principales: Carlisle, Rachel E., Brimble, Elise, Werner, Kaitlyn E., Cruz, Gaile L., Ask, Kjetil, Ingram, Alistair J., Dickhout, Jeffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885586/
https://www.ncbi.nlm.nih.gov/pubmed/24416259
http://dx.doi.org/10.1371/journal.pone.0084663

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