A Modified TALEN-Based Strategy for Rapidly and Efficiently Generating Knockout Mice for Kidney Development Studies

The transcription activator-like effector nucleases (TALENs) strategy has been widely used to delete and mutate genes in vitro. This strategy has begun to be used for in vivo systemic gene manipulation, but not in an organ-specific manner. In this study, we developed a modified, highly efficient TAL...

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Detalles Bibliográficos
Autores principales: Liu, Yunhong, Lv, Xiaoyan, Tan, Ruizhi, Liu, Tianming, Chen, Tielin, Li, Mi, Liu, Yuhang, Nie, Fang, Wang, Xiaoyan, Zhou, Puhui, Chen, Mianzhi, Zhou, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885652/
https://www.ncbi.nlm.nih.gov/pubmed/24416307
http://dx.doi.org/10.1371/journal.pone.0084893

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