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β-adrenergic receptor responsiveness in aging heart and clinical implications
Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the so called “β-adrenergic desensitization”). Adr...
Autores principales: | Ferrara, Nicola, Komici, Klara, Corbi, Graziamaria, Pagano, Gennaro, Furgi, Giuseppe, Rengo, Carlo, Femminella, Grazia D., Leosco, Dario, Bonaduce, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885807/ https://www.ncbi.nlm.nih.gov/pubmed/24409150 http://dx.doi.org/10.3389/fphys.2013.00396 |
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