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Giant Cell Fibroma in Children: Report of Two Cases and Literature Review

BACKGROUND: Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the free gingiva of a 7 and 6 year old boys. METHOD...

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Autores principales: Nikitakis, Nikolaos G., Emmanouil, Dimitris, Maroulakos, Michail P., Angelopoulou, Matina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Stilus Optimus 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886105/
https://www.ncbi.nlm.nih.gov/pubmed/24422028
http://dx.doi.org/10.5037/jomr.2013.4105
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author Nikitakis, Nikolaos G.
Emmanouil, Dimitris
Maroulakos, Michail P.
Angelopoulou, Matina V.
author_facet Nikitakis, Nikolaos G.
Emmanouil, Dimitris
Maroulakos, Michail P.
Angelopoulou, Matina V.
author_sort Nikitakis, Nikolaos G.
collection PubMed
description BACKGROUND: Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the free gingiva of a 7 and 6 year old boys. METHODS: Both nodules were presented in the mandibular anterior region. In the differential diagnosis several fibrous hyperplastic lesions were considered such as traumatic fibroma, papilloma, peripheral ossifying fibroma, peripheral odontogenic fibroma, giant cell fibroma and odontogenic hamartoma. RESULTS: The lesions were removed and the histological examination revealed fibrocollagenous connective tissue with the presence of stellate giant cells which confirmed the diagnosis of giant cell fibroma. CONCLUSIONS: Dentists should be aware of the existence of giant cell fibroma in children, which must be included in the differential diagnosis of nodular lesions of the gingiva and adequately diagnosed and treated by removal and histopathological examination.
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spelling pubmed-38861052014-01-13 Giant Cell Fibroma in Children: Report of Two Cases and Literature Review Nikitakis, Nikolaos G. Emmanouil, Dimitris Maroulakos, Michail P. Angelopoulou, Matina V. J Oral Maxillofac Res Case Report BACKGROUND: Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the free gingiva of a 7 and 6 year old boys. METHODS: Both nodules were presented in the mandibular anterior region. In the differential diagnosis several fibrous hyperplastic lesions were considered such as traumatic fibroma, papilloma, peripheral ossifying fibroma, peripheral odontogenic fibroma, giant cell fibroma and odontogenic hamartoma. RESULTS: The lesions were removed and the histological examination revealed fibrocollagenous connective tissue with the presence of stellate giant cells which confirmed the diagnosis of giant cell fibroma. CONCLUSIONS: Dentists should be aware of the existence of giant cell fibroma in children, which must be included in the differential diagnosis of nodular lesions of the gingiva and adequately diagnosed and treated by removal and histopathological examination. Stilus Optimus 2013-04-01 /pmc/articles/PMC3886105/ /pubmed/24422028 http://dx.doi.org/10.5037/jomr.2013.4105 Text en Copyright © Nikitakis NG, Emmanouil D, Maroulakos MP, Angelopoulou MV. Published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH (http://www.ejomr.org), 1 April 2013. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article, first published in the JOURNAL OF ORAL & MAXILLOFACIAL RESEARCH, distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work and is properly cited. The copyright, license information and link to the original publication on http://www.ejomr.org must be included.
spellingShingle Case Report
Nikitakis, Nikolaos G.
Emmanouil, Dimitris
Maroulakos, Michail P.
Angelopoulou, Matina V.
Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title_full Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title_fullStr Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title_full_unstemmed Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title_short Giant Cell Fibroma in Children: Report of Two Cases and Literature Review
title_sort giant cell fibroma in children: report of two cases and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886105/
https://www.ncbi.nlm.nih.gov/pubmed/24422028
http://dx.doi.org/10.5037/jomr.2013.4105
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