Fetal Wound Healing Biomarkers

Fetal skin has the intrinsic capacity for wound healing, which is not correlated with the intrauterine environment. This intrinsic ability requires biochemical signals, which start at the cellular level and lead to secretion of transforming factors and expression of receptors, and specific markers t...

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Detalles Bibliográficos
Autores principales: Helmo, Fernanda Rodrigues, Machado, Juliana Reis, Guimarães, Camila Souza de Oliveira, Teixeira, Vicente de Paula Antunes, dos Reis, Marlene Antônia, Corrêa, Rosana Rosa Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886274/
https://www.ncbi.nlm.nih.gov/pubmed/24427782
http://dx.doi.org/10.1155/2013/567353
Descripción
Sumario:Fetal skin has the intrinsic capacity for wound healing, which is not correlated with the intrauterine environment. This intrinsic ability requires biochemical signals, which start at the cellular level and lead to secretion of transforming factors and expression of receptors, and specific markers that promote wound healing without scar formation. The mechanisms and molecular pathways of wound healing still need to be elucidated to achieve a complete understanding of this remodeling system. The aim of this paper is to discuss the main biomarkers involved in fetal skin wound healing as well as their respective mechanisms of action.

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