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The Peculiar Epidemiology of Dracunculiasis in Chad

Dracunculiasis was rediscovered in Chad in 2010 after an apparent absence of 10 years. In April 2012 active village-based surveillance was initiated to determine where, when, and how transmission of the disease was occurring, and to implement interventions to interrupt it. The current epidemiologic...

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Autores principales: Eberhard, Mark L., Ruiz-Tiben, Ernesto, Hopkins, Donald R., Farrell, Corey, Toe, Fernand, Weiss, Adam, Withers, P. Craig, Jenks, M. Harley, Thiele, Elizabeth A., Cotton, James A., Hance, Zahra, Holroyd, Nancy, Cama, Vitaliano A., Tahir, Mahamat Ali, Mounda, Tchonfienet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886430/
https://www.ncbi.nlm.nih.gov/pubmed/24277785
http://dx.doi.org/10.4269/ajtmh.13-0554
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author Eberhard, Mark L.
Ruiz-Tiben, Ernesto
Hopkins, Donald R.
Farrell, Corey
Toe, Fernand
Weiss, Adam
Withers, P. Craig
Jenks, M. Harley
Thiele, Elizabeth A.
Cotton, James A.
Hance, Zahra
Holroyd, Nancy
Cama, Vitaliano A.
Tahir, Mahamat Ali
Mounda, Tchonfienet
author_facet Eberhard, Mark L.
Ruiz-Tiben, Ernesto
Hopkins, Donald R.
Farrell, Corey
Toe, Fernand
Weiss, Adam
Withers, P. Craig
Jenks, M. Harley
Thiele, Elizabeth A.
Cotton, James A.
Hance, Zahra
Holroyd, Nancy
Cama, Vitaliano A.
Tahir, Mahamat Ali
Mounda, Tchonfienet
author_sort Eberhard, Mark L.
collection PubMed
description Dracunculiasis was rediscovered in Chad in 2010 after an apparent absence of 10 years. In April 2012 active village-based surveillance was initiated to determine where, when, and how transmission of the disease was occurring, and to implement interventions to interrupt it. The current epidemiologic pattern of the disease in Chad is unlike that seen previously in Chad or other endemic countries, i.e., no clustering of cases by village or association with a common water source, the average number of worms per person was small, and a large number of dogs were found to be infected. Molecular sequencing suggests these infections were all caused by Dracunculus medinensis. It appears that the infection in dogs is serving as the major driving force sustaining transmission in Chad, that an aberrant life cycle involving a paratenic host common to people and dogs is occurring, and that the cases in humans are sporadic and incidental.
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spelling pubmed-38864302014-01-10 The Peculiar Epidemiology of Dracunculiasis in Chad Eberhard, Mark L. Ruiz-Tiben, Ernesto Hopkins, Donald R. Farrell, Corey Toe, Fernand Weiss, Adam Withers, P. Craig Jenks, M. Harley Thiele, Elizabeth A. Cotton, James A. Hance, Zahra Holroyd, Nancy Cama, Vitaliano A. Tahir, Mahamat Ali Mounda, Tchonfienet Am J Trop Med Hyg Articles Dracunculiasis was rediscovered in Chad in 2010 after an apparent absence of 10 years. In April 2012 active village-based surveillance was initiated to determine where, when, and how transmission of the disease was occurring, and to implement interventions to interrupt it. The current epidemiologic pattern of the disease in Chad is unlike that seen previously in Chad or other endemic countries, i.e., no clustering of cases by village or association with a common water source, the average number of worms per person was small, and a large number of dogs were found to be infected. Molecular sequencing suggests these infections were all caused by Dracunculus medinensis. It appears that the infection in dogs is serving as the major driving force sustaining transmission in Chad, that an aberrant life cycle involving a paratenic host common to people and dogs is occurring, and that the cases in humans are sporadic and incidental. The American Society of Tropical Medicine and Hygiene 2014-01-08 /pmc/articles/PMC3886430/ /pubmed/24277785 http://dx.doi.org/10.4269/ajtmh.13-0554 Text en ©The American Society of Tropical Medicine and Hygiene This is an Open Access article distributed under the terms of the American Society of Tropical Medicine and Hygiene's Re-use License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Eberhard, Mark L.
Ruiz-Tiben, Ernesto
Hopkins, Donald R.
Farrell, Corey
Toe, Fernand
Weiss, Adam
Withers, P. Craig
Jenks, M. Harley
Thiele, Elizabeth A.
Cotton, James A.
Hance, Zahra
Holroyd, Nancy
Cama, Vitaliano A.
Tahir, Mahamat Ali
Mounda, Tchonfienet
The Peculiar Epidemiology of Dracunculiasis in Chad
title The Peculiar Epidemiology of Dracunculiasis in Chad
title_full The Peculiar Epidemiology of Dracunculiasis in Chad
title_fullStr The Peculiar Epidemiology of Dracunculiasis in Chad
title_full_unstemmed The Peculiar Epidemiology of Dracunculiasis in Chad
title_short The Peculiar Epidemiology of Dracunculiasis in Chad
title_sort peculiar epidemiology of dracunculiasis in chad
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886430/
https://www.ncbi.nlm.nih.gov/pubmed/24277785
http://dx.doi.org/10.4269/ajtmh.13-0554
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