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Multipyrene Tandem Probes for Point Mutations Detection in DNA

Here we report design, synthesis and characterization of highly sensitive, specific and stable in biological systems fluorescent probes for point mutation detection in DNA. The tandems of 3′- and 5′-mono- and bis-pyrene conjugated oligo(2′-O-methylribonucleotides), protected by 3′-“inverted” thymidi...

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Detalles Bibliográficos
Autores principales:	Kholodar, Svetlana A., Novopashina, Darya S., Meschaninova, Mariya I., Venyaminova, Alya G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886547/ https://www.ncbi.nlm.nih.gov/pubmed/24455205 http://dx.doi.org/10.1155/2013/860457

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