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Tregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?

Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were discovered in the heavy and light chains of IgG (De Groot et al. Blood, 2008). When added ex vivo to human PBMCs, these Tregitopes activated regulatory T cells...

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Detalles Bibliográficos
Autores principales: De Groot, Anne S., Cousens, Leslie, Mingozzi, Federico, Martin, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886585/
https://www.ncbi.nlm.nih.gov/pubmed/24454476
http://dx.doi.org/10.1155/2013/493138