Toll‐Like Receptor‐2 Mediates Adaptive Cardiac Hypertrophy in Response to Pressure Overload Through Interleukin‐1β Upregulation via Nuclear Factor κB Activation

BACKGROUND: Inflammation is induced in the heart during the development of cardiac hypertrophy. The initiating mechanisms and the role of inflammation in cardiac hypertrophy, however, remain unclear. Toll‐like receptor‐2 (TLR2) recognizes endogenous molecules that induce noninfectious inflammation....

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Detalles Bibliográficos
Autores principales: Higashikuni, Yasutomi, Tanaka, Kimie, Kato, Megumi, Nureki, Osamu, Hirata, Yasunobu, Nagai, Ryozo, Komuro, Issei, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886766/
https://www.ncbi.nlm.nih.gov/pubmed/24249711
http://dx.doi.org/10.1161/JAHA.113.000267

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