Mechanisms With Clinical Implications for Atrial Fibrillation–Associated Remodeling: Cathepsin K Expression, Regulation, and Therapeutic Target and Biomarker

BACKGROUND: The cysteine protease cathepsin K (CatK) has been implicated in the pathogenesis of cardiovascular disease. We sought to determine the link between atrial fibrillation (AF) and plasma CatK levels and to investigate the expression of and therapeutic target for CatK in vivo and in vitro. M...

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Detalles Bibliográficos
Autores principales: Fujita, Masaya, Cheng, Xian Wu, Inden, Yasuya, Shimano, Masayuki, Yoshida, Naoki, Inoue, Aiko, Yamamoto, Toshihiko, Takeshita, Kyosuke, Kyo, Seifuku, Taguchi, Noriko, Shi, Guo‐Ping, Kuzuya, Masafumi, Okumura, Kenji, Murohara, Toyoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886768/
https://www.ncbi.nlm.nih.gov/pubmed/24342995
http://dx.doi.org/10.1161/JAHA.113.000503

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