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Buffering the pH of the culture medium does not extend yeast replicative lifespan

During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study...

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Detalles Bibliográficos
Autores principales: Wasko, Brian M, Carr, Daniel T, Tung, Herman, Doan, Ha, Schurman, Nathan, Neault, Jillian R, Feng, Joey, Lee, Janet, Zipkin, Ben, Mouser, Jacob, Oudanonh, Edward, Nguyen, Tina, Stetina, Torin, Shemorry, Anna, Lemma, Mekedes, Kaeberlein, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886788/
https://www.ncbi.nlm.nih.gov/pubmed/24555104
http://dx.doi.org/10.12688/f1000research.2-216.v1

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