Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants

Johne's disease (JD), a persistent and slow progressing infection of ruminants such as cows and sheep, is caused by slow replicating bacilli Mycobacterium avium subspecies paratuberculosis (MAP) infecting macrophages in the gut. Infected animals initially mount a cell-mediated CD4 T cell respon...

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Detalles Bibliográficos
Autores principales: Magombedze, Gesham, Eda, Shigetoshi, Ganusov, Vitaly V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886887/
https://www.ncbi.nlm.nih.gov/pubmed/24415928
http://dx.doi.org/10.1371/journal.pcbi.1003414

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