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p53 and TAp63 Promote Keratinocyte Proliferation and Differentiation in Breeding Tubercles of the Zebrafish
p63 is a multi-isoform member of the p53 family of transcription factors. There is compelling genetic evidence that ΔNp63 isoforms are needed for keratinocyte proliferation and stemness in the developing vertebrate epidermis. However, the role of TAp63 isoforms is not fully understood, and TAp63 kno...
Autores principales: | Fischer, Boris, Metzger, Manuel, Richardson, Rebecca, Knyphausen, Philipp, Ramezani, Thomas, Franzen, Rainer, Schmelzer, Elmon, Bloch, Wilhelm, Carney, Thomas J., Hammerschmidt, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886889/ https://www.ncbi.nlm.nih.gov/pubmed/24415949 http://dx.doi.org/10.1371/journal.pgen.1004048 |
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