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Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni

OBJECTIVES: CmeABC is a resistance-nodulation-cell division (RND)-type multidrug efflux pump conferring resistance to clinically important antibiotics in Campylobacter. This study aimed to identify the optimal target sites for the inhibition of CmeABC with antisense peptide nucleic acid (PNA). METHO...

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Detalles Bibliográficos
Autores principales:	Oh, Euna, Zhang, Qijing, Jeon, Byeonghwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886934/ https://www.ncbi.nlm.nih.gov/pubmed/24084637 http://dx.doi.org/10.1093/jac/dkt381

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