Stable Expression of Human Muscle-Specific Kinase in HEp-2 M4 Cells for Automatic Immunofluorescence Diagnostics of Myasthenia Gravis

Muscle-specific kinase (MuSK) belongs to the nicotinic acetylcholine receptor complex which is targeted by pathogenic autoantibodies causing Myasthenia gravis. While up to 95% of patients with generalized Myasthenia gravis were shown to be positive for acetylcholine receptor-specific autoantibodies,...

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Detalles Bibliográficos
Autores principales: George, Sandra, Paulick, Silvia, Knütter, Ilka, Röber, Nadja, Hiemann, Rico, Roggenbuck, Dirk, Conrad, Karsten, Küpper, Jan-Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886972/
https://www.ncbi.nlm.nih.gov/pubmed/24416182
http://dx.doi.org/10.1371/journal.pone.0083924

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