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Altered Mitochondria Morphology and Cell Metabolism in Apaf1-Deficient Cells

BACKGROUND: Apaf1 (apoptotic protease activating factor 1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. Other cellular roles, including a pro-survival role, have...

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Detalles Bibliográficos
Autores principales:	Sancho, Mónica, Gortat, Anna, Herrera, Andrés E., Andreu-Fernández, Vicente, Ferraro, Elisabetta, Cecconi, Francesco, Orzáez, Mar, Pérez-Payá, Enrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886985/ https://www.ncbi.nlm.nih.gov/pubmed/24416260 http://dx.doi.org/10.1371/journal.pone.0084666

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