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Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dynamics of ART-induced reductions in viral RNA (vRNA...

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Detalles Bibliográficos
Autores principales: Denton, Paul W., Long, Julie M., Wietgrefe, Stephen W., Sykes, Craig, Spagnuolo, Rae Ann, Snyder, Olivia D., Perkey, Katherine, Archin, Nancie M., Choudhary, Shailesh K., Yang, Kuo, Hudgens, Michael G., Pastan, Ira, Haase, Ashley T., Kashuba, Angela D., Berger, Edward A., Margolis, David M., Garcia, J. Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887103/
https://www.ncbi.nlm.nih.gov/pubmed/24415939
http://dx.doi.org/10.1371/journal.ppat.1003872