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Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1

The transcription factor FOXP1 is implicated in the pathogenesis of B-cell lymphomas through chromosomal translocations involving either immunoglobulin heavy chain (IGH) locus or non-IG sequences. The former translocation, t(3;14)(p13;q32), results in dysregulated expression of FOXP1 juxtaposed with...

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Detalles Bibliográficos
Autores principales: Rouhigharabaei, Leila, Finalet Ferreiro, Julio, Tousseyn, Thomas, van der Krogt, Jo-Anne, Put, Natalie, Haralambieva, Eugenia, Graux, Carlos, Maes, Brigitte, Vicente, Carmen, Vandenberghe, Peter, Cools, Jan, Wlodarska, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887110/
https://www.ncbi.nlm.nih.gov/pubmed/24416450
http://dx.doi.org/10.1371/journal.pone.0085851