Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology

Understanding the formation and propagation of aggregates of the Alzheimer disease-associated Tau protein in vivo is vital for the development of therapeutics for this devastating disorder. Using our recently developed live-cell aggregation sensor in neuron-like cells, we demonstrate that different...

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Detalles Bibliográficos
Autores principales: Michel, Claire H., Kumar, Satish, Pinotsi, Dorothea, Tunnacliffe, Alan, St. George-Hyslop, Peter, Mandelkow, Eckhard, Mandelkow, Eva-Maria, Kaminski, Clemens F., Kaminski Schierle, Gabriele S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887218/
https://www.ncbi.nlm.nih.gov/pubmed/24235150
http://dx.doi.org/10.1074/jbc.M113.515445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887218/
https://www.ncbi.nlm.nih.gov/pubmed/24235150
http://dx.doi.org/10.1074/jbc.M113.515445

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