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Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011

BACKGROUND: Cutaneous leishmaniasis (CL) is a major health problem in many parts of Iran, although diagnosis of CL especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. Diagnosis of CL in non-endemic area is not as simple as in endemic foci. In this...

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Autores principales: MOHAMMADI, Akram MIR AMIN, KHAMESIPOUR, Ali, KHATAMI, Alireza, JAVADI, Amir, NASSIRI-KASHANI, Mansour, FIROOZ, Alireza, DOWLATI, Yahya, BEHNIA, Massoud, ESKANDARI, Seyyed Ebrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887245/
https://www.ncbi.nlm.nih.gov/pubmed/24454437
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author MOHAMMADI, Akram MIR AMIN
KHAMESIPOUR, Ali
KHATAMI, Alireza
JAVADI, Amir
NASSIRI-KASHANI, Mansour
FIROOZ, Alireza
DOWLATI, Yahya
BEHNIA, Massoud
ESKANDARI, Seyyed Ebrahim
author_facet MOHAMMADI, Akram MIR AMIN
KHAMESIPOUR, Ali
KHATAMI, Alireza
JAVADI, Amir
NASSIRI-KASHANI, Mansour
FIROOZ, Alireza
DOWLATI, Yahya
BEHNIA, Massoud
ESKANDARI, Seyyed Ebrahim
author_sort MOHAMMADI, Akram MIR AMIN
collection PubMed
description BACKGROUND: Cutaneous leishmaniasis (CL) is a major health problem in many parts of Iran, although diagnosis of CL especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. Diagnosis of CL in non-endemic area is not as simple as in endemic foci. In this study, the status and the proportions of CL induced by Leishmania major and L. tropica among CL suspected patients referred to the Center for Research and Training in Skin Diseases and Leprosy, (CRTSDL) during 2008 to 2011 are described. METHODS: CL patients with suspected lesions were clinically examined. History of trip to zoonotic CL and/or anthroponotic CL endemic areas and the characteristics of their lesion(s) were recorded. Diagnosis of the lesion was done using direct smear microscopy, culture and conventional polymerase chain reaction (PCR). RESULTS: A total of 404 (M = 256, F = 148) patients with 776 lesions were recruited and parasitologically examined. The results showed that 255 of the patients with 613 lesions; patients with lesion(s) induced by L. major=147 (M = 63, 43%, F = 84, 57%) and lesion(s) induced by L. tropica=108 (M = 35, 32%, F = 73, 68%). History of travel to endemic area was not always correlated with isolated Leishmania species. CONCLUSION: Although travel history to endemic area is an important factor to be considered for diagnosis, but parasitological confirmation is necessary initiation of treatment.
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spelling pubmed-38872452014-01-21 Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011 MOHAMMADI, Akram MIR AMIN KHAMESIPOUR, Ali KHATAMI, Alireza JAVADI, Amir NASSIRI-KASHANI, Mansour FIROOZ, Alireza DOWLATI, Yahya BEHNIA, Massoud ESKANDARI, Seyyed Ebrahim Iran J Parasitol Original Article BACKGROUND: Cutaneous leishmaniasis (CL) is a major health problem in many parts of Iran, although diagnosis of CL especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. Diagnosis of CL in non-endemic area is not as simple as in endemic foci. In this study, the status and the proportions of CL induced by Leishmania major and L. tropica among CL suspected patients referred to the Center for Research and Training in Skin Diseases and Leprosy, (CRTSDL) during 2008 to 2011 are described. METHODS: CL patients with suspected lesions were clinically examined. History of trip to zoonotic CL and/or anthroponotic CL endemic areas and the characteristics of their lesion(s) were recorded. Diagnosis of the lesion was done using direct smear microscopy, culture and conventional polymerase chain reaction (PCR). RESULTS: A total of 404 (M = 256, F = 148) patients with 776 lesions were recruited and parasitologically examined. The results showed that 255 of the patients with 613 lesions; patients with lesion(s) induced by L. major=147 (M = 63, 43%, F = 84, 57%) and lesion(s) induced by L. tropica=108 (M = 35, 32%, F = 73, 68%). History of travel to endemic area was not always correlated with isolated Leishmania species. CONCLUSION: Although travel history to endemic area is an important factor to be considered for diagnosis, but parasitological confirmation is necessary initiation of treatment. Tehran University of Medical Sciences 2013 /pmc/articles/PMC3887245/ /pubmed/24454437 Text en © 2013 Iranian Society of Parasitology & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
MOHAMMADI, Akram MIR AMIN
KHAMESIPOUR, Ali
KHATAMI, Alireza
JAVADI, Amir
NASSIRI-KASHANI, Mansour
FIROOZ, Alireza
DOWLATI, Yahya
BEHNIA, Massoud
ESKANDARI, Seyyed Ebrahim
Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title_full Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title_fullStr Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title_full_unstemmed Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title_short Cutaneous Leishmaniasis in Suspected Patients Referred To the Center for Research and Training in Skin Diseases and Leprosy, Tehran, Iran from 2008 To 2011
title_sort cutaneous leishmaniasis in suspected patients referred to the center for research and training in skin diseases and leprosy, tehran, iran from 2008 to 2011
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887245/
https://www.ncbi.nlm.nih.gov/pubmed/24454437
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