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The potential application of a transcriptionally regulated oncolytic herpes simplex virus for human cancer therapy

BACKGROUND: Emerging studies have shown the potential benefit of arming oncolytic viruses with therapeutic genes. However, most of these therapeutic genes are placed under the regulation of ubiquitous viral promoters. Our goal is to generate a safer yet potent oncolytic herpes simplex virus type-1 (...

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Detalles Bibliográficos
Autores principales:	Miao, L, Fraefel, C, Sia, K C, Newman, J P, Mohamed-Bashir, S A, Ng, W H, Lam, P Y P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887293/ https://www.ncbi.nlm.nih.gov/pubmed/24196790 http://dx.doi.org/10.1038/bjc.2013.692

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