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Generation of a Useful roX1 Allele by Targeted Gene Conversion

Methods for altering the sequence of endogenous Drosophila melanogaster genes remain labor-intensive. We have tested a relatively simple strategy that enables the introduction of engineered mutations in the vicinity of existing P-elements. This method was used to generate useful alleles of the roX1...

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Detalles Bibliográficos
Autores principales: Apte, Manasi S., Moran, Victoria A., Menon, Debashish U., Rattner, Barbara P., Barry, Kathryn Hughes, Zunder, Rachel M., Kelley, Richard, Meller, Victoria H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887531/
https://www.ncbi.nlm.nih.gov/pubmed/24281425
http://dx.doi.org/10.1534/g3.113.008508

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