Cargando…

Chemical Suppression of Defects in Mitotic Spindle Assembly, Redox Control, and Sterol Biosynthesis by Hydroxyurea

We describe the results of a systematic search for a class of hitherto-overlooked chemical-genetic interactions in the Saccharomyces cerevisiae genome, which exists between a detrimental genetic mutation and a chemical/drug that can ameliorate, rather than exacerbate, that detriment. We refer to thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCulley, Andrew, Haarer, Brian, Viggiano, Susan, Karchin, Joshua, Feng, Wenyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2013
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887538/ https://www.ncbi.nlm.nih.gov/pubmed/24192836 http://dx.doi.org/10.1534/g3.113.009100

Ejemplares similares

Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription
por: Hoffman, Elizabeth A., et al.
Publicado: (2015)

Phospho‐regulation of mitotic spindle assembly
por: Ong, Joseph Y., et al.
Publicado: (2020)

On the assembly of the mitotic spindle, bistability and hysteresis
por: Serpico, Angela Flavia, et al.
Publicado: (2023)

Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe
por: Yukawa, Masashi, et al.
Publicado: (2018)

In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint
por: Ibrahim, Bashar, et al.
Publicado: (2008)

Membrane-based mechanisms of mitotic spindle assembly
por: Schweizer, Nina, et al.
Publicado: (2015)

Regulation of mitotic progression by the spindle assembly checkpoint
por: Lischetti, Tiziana, et al.
Publicado: (2015)

Mitotic progression and dual spindle formation caused by spindle association of de novo–formed microtubule-organizing centers in parthenogenetic embryos of Drosophila ananassae
por: Hirai, Kazuyuki, et al.
Publicado: (2022)

Mitotic spindle assembly by two different pathways in vitro
Publicado: (1991)

Poleward microtubule flux mitotic spindles assembled in vitro
Publicado: (1991)

Kinesin-related proteins required for assembly of the mitotic spindle
Publicado: (1992)

Relative contributions of chromatin and kinetochores to mitotic spindle assembly
por: O'Connell, Christopher B., et al.
Publicado: (2009)

Mitotic Spindle Assembly in Land Plants: Molecules and Mechanisms
por: Yamada, Moé, et al.
Publicado: (2017)

Microtubule pivoting enables mitotic spindle assembly in S. cerevisiae
por: Fong, Kimberly K., et al.
Publicado: (2021)

Linking Genetics to Structural Biology: Complex Heterozygosity Screening with Actin Alanine Scan Alleles Identifies Functionally Related Surfaces on Yeast Actin
por: DiPrima, Stephanie, et al.
Publicado: (2014)

Actin Dosage Lethality Screening in Yeast Mediated by Selective Ploidy Ablation Reveals Links to Urmylation/Wobble Codon Recognition and Chromosome Stability
por: Haarer, Brian, et al.
Publicado: (2013)

Centromeric Barrier Disruption Leads to Mitotic Defects in Schizosaccharomyces pombe
por: Gaither, Terilyn L., et al.
Publicado: (2014)

Transient defects of mitotic spindle geometry and chromosome segregation errors
por: Silkworth, William T, et al.
Publicado: (2012)

A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle
por: Horne, Melinda M., et al.
Publicado: (2003)

Spatio-temporal Model for Silencing of the Mitotic Spindle Assembly Checkpoint
por: Chen, Jing, et al.
Publicado: (2014)

The Prp19 Complex Directly Functions in Mitotic Spindle Assembly
por: Hofmann, Jennifer C., et al.
Publicado: (2013)

The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly
por: Labbé, Jean-Claude, et al.
Publicado: (2004)

Concentrating on the mitotic spindle
por: Maddox, Paul S., et al.
Publicado: (2015)

Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae
por: Arsenault, Heather E, et al.
Publicado: (2021)

Inhibition of spindle extension through the yeast S phase checkpoint is coupled to replication fork stability and the integrity of centromeric DNA
por: Julius, Jeff, et al.
Publicado: (2019)

Thirty years of search and capture: The complex simplicity of mitotic spindle assembly
por: Heald, Rebecca, et al.
Publicado: (2015)

Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus
por: Grenfell, Andrew W., et al.
Publicado: (2016)

Mitotic Protein Kinase 1: Role in Spindle Assembly Checkpoint Revisited
por: Tandle, Anita, et al.
Publicado: (2016)

Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast
por: Blackwell, Robert, et al.
Publicado: (2017)

Regulation of mitotic spindle assembly factor NuMA by Importin-β
por: Chang, Chih-Chia, et al.
Publicado: (2017)

Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment
por: Bennabi, Isma, et al.
Publicado: (2018)

Suppression of ectopic assembly of centriole proteins ensures mitotic spindle integrity
por: Shiratsuchi, Gen, et al.
Publicado: (2015)

Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression
por: O’Regan, Laura, et al.
Publicado: (2015)

Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast
por: Tang, Ngang Heok, et al.
Publicado: (2014)

Biosynthesis of Cholesterol and Other Sterols
por: Nes, W. David
Publicado: (2011)

Force and the spindle: Mechanical cues in mitotic spindle orientation
por: Nestor-Bergmann, Alexander, et al.
Publicado: (2014)

ACTIN AND MYOSIN IN THE MITOTIC SPINDLE
por: Robinson, Richard
Publicado: (2008)

Cell division and the mitotic spindle
por: Inoue, S.
Publicado: (1981)

Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle
por: Rogers, Stephen L., et al.
Publicado: (2002)

Spindle assembly checkpoint is sufficient for complete Cdc20 sequestering in mitotic control
por: Ibrahim, Bashar
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1uc1macm25o1q4tb5r74g8955u