Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis

Mycobacterium tuberculosis is successfully evolving antibiotic resistance, threatening attempts at tuberculosis epidemic control. Mechanisms of resistance, including the genetic changes favored by selection in resistant isolates, are incompletely understood. Using 116 newly and 7 previously sequence...

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Detalles Bibliográficos
Autores principales: Farhat, Maha R, Shapiro, B Jesse, Kieser, Karen J, Sultana, Razvan, Jacobson, Karen R, Victor, Thomas C, Warren, Robin M, Streicher, Elizabeth M, Calver, Alistair, Sloutsky, Alex, Kaur, Devinder, Posey, Jamie E, Plikaytis, Bonnie, Oggioni, Marco R, Gardy, Jennifer L, Johnston, James C, Rodrigues, Mabel, Tang, Patrick K C, Kato-Maeda, Midori, Borowsky, Mark L, Muddukrishna, Bhavana, Kreiswirth, Barry N, Kurepina, Natalia, Galagan, James, Gagneux, Sebastien, Birren, Bruce, Rubin, Eric J, Lander, Eric S, Sabeti, Pardis C, Murray, Megan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887553/
https://www.ncbi.nlm.nih.gov/pubmed/23995135
http://dx.doi.org/10.1038/ng.2747

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