A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy

OBJECTIVES: Intrahepatic cholestasis of pregnancy (ICP) has a complex etiology with a significant genetic component. Heterozygous mutations of canalicular transporters occur in a subset of ICP cases and a population susceptibility allele (p.444A) has been identified in ABCB11. We sought to expand ou...

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Detalles Bibliográficos
Autores principales: Dixon, Peter H, Wadsworth, Christopher A, Chambers, Jennifer, Donnelly, Jennifer, Cooley, Sharon, Buckley, Rebecca, Mannino, Ramona, Jarvis, Sheba, Syngelaki, Argyro, Geenes, Victoria, Paul, Priyadarshini, Sothinathan, Meera, Kubitz, Ralf, Lammert, Frank, Tribe, Rachel M, Ch'ng, Chin Lye, Marschall, Hanns-Ulrich, Glantz, Anna, Khan, Shahid A, Nicolaides, Kypros, Whittaker, John, Geary, Michael, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Liver
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887577/
https://www.ncbi.nlm.nih.gov/pubmed/24366234
http://dx.doi.org/10.1038/ajg.2013.406

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