Visualization of Sialidase Activity in Mammalian Tissues and Cancer Detection with a Novel Fluorescent Sialidase Substrate

Sialidase removes sialic acid from sialoglycoconjugates and plays crucial roles in many physiological and pathological processes. Various human cancers express an abnormally high level of the plasma membrane-associated sialidase isoform.Visualization of sialidase activity in living mammalian tissues...

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Detalles Bibliográficos
Autores principales: Minami, Akira, Otsubo, Tadamune, Ieno, Daisuke, Ikeda, Kiyoshi, Kanazawa, Hiroaki, Shimizu, Kosuke, Ohata, Ko, Yokochi, Tsunehiro, Horii, Yuuki, Fukumoto, Hokuto, Taguchi, Risa, Takahashi, Tadanobu, Oku, Naoto, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888388/
https://www.ncbi.nlm.nih.gov/pubmed/24427265
http://dx.doi.org/10.1371/journal.pone.0081941

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