Gene and MicroRNA Transcriptome Analysis of Parkinson's Related LRRK2 Mouse Models

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent cause of genetic Parkinson’s disease (PD). The biological function of LRRK2 and how mutations lead to disease remain poorly defined. It has been proposed that LRRK2 could function in gene transcription regulation; however, this...

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Detalles Bibliográficos
Autores principales: Dorval, Véronique, Mandemakers, Wim, Jolivette, Francis, Coudert, Laetitia, Mazroui, Rachid, De Strooper, Bart, Hébert, Sébastien S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888428/
https://www.ncbi.nlm.nih.gov/pubmed/24427314
http://dx.doi.org/10.1371/journal.pone.0085510

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