Pharmacogenomic characterization of gemcitabine response – a framework for data integration to enable personalized medicine

OBJECTIVES: Response to the oncology drug gemcitabine may be variable in part due to genetic differences in the enzymes and transporters responsible for its metabolism and disposition. The aim of our in-silico study was to identify gene variants significantly associated with gemcitabine response tha...

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Detalles Bibliográficos
Autores principales: Harris, Michael, Bhuvaneshwar, Krithika, Natarajan, Thanemozhi, Sheahan, Laura, Wang, Difei, Tadesse, Mahlet G., Shoulson, Ira, Filice, Ross, Steadman, Kenneth, Pishvaian, Michael J., Madhavan, Subha, Deeken, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888473/
https://www.ncbi.nlm.nih.gov/pubmed/24401833
http://dx.doi.org/10.1097/FPC.0000000000000015

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