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Effect of different imputation approaches on the evaluation of radiographic progression in patients with psoriatic arthritis: results of the RAPID-PsA 24-week phase III double-blind randomised placebo-controlled study of certolizumab pegol
OBJECTIVES: To report the effect of different imputation methodologies on the assessment of radiographic progression in clinical trials. METHODS: The 216-week RAPID-psoriatic arthritis (PsA) (NCT01087788) trial of certolizumab pegol (CZP) in patients with active PsA was double-blind and placebo-cont...
Autores principales: | van der Heijde, D, Fleischmann, R, Wollenhaupt, J, Deodhar, A, Kielar, D, Woltering, F, Stach, C, Hoepken, B, Arledge, T, Mease, P J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888591/ https://www.ncbi.nlm.nih.gov/pubmed/23942869 http://dx.doi.org/10.1136/annrheumdis-2013-203697 |
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