Effect of Complexation with Arabinogalactan on Pharmacokinetics of “Guest” Drugs in Rats: For Example, Warfarin

A pharmacokinetic study of the warfarin (WF) : arabinogalactan (AG) complex with the 1 : 10 mass ratio after its intragastric introduction to Wistar rats at a dose of 5 mg/kg (WF dose in the complex was 0.5 mg/kg) once a day for three days was conducted. It was found that C (max), T (1/2), and AUC o...

Descripción completa

Detalles Bibliográficos
Autores principales: Khvostov, Mikhail V., Chernonosov, Alexander A., Tolstikova, Tatjana G., Kasakin, Marat F., Fedorova, Olga S., Dushkin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888672/
https://www.ncbi.nlm.nih.gov/pubmed/24455672
http://dx.doi.org/10.1155/2013/156381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888672/
https://www.ncbi.nlm.nih.gov/pubmed/24455672
http://dx.doi.org/10.1155/2013/156381

Ejemplares similares