Cargando…
Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas
The neural mechanisms underlying the spontaneous, stimulus-independent emergence of intentions and decisions to act are poorly understood. Using a neurobiologically realistic model of frontal and temporal areas of the brain, we simulated the learning of perception–action circuits for speech and hand...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888926/ https://www.ncbi.nlm.nih.gov/pubmed/23489583 http://dx.doi.org/10.1016/j.bandl.2013.02.001 |
_version_ | 1782299129629638656 |
---|---|
author | Garagnani, Max Pulvermüller, Friedemann |
author_facet | Garagnani, Max Pulvermüller, Friedemann |
author_sort | Garagnani, Max |
collection | PubMed |
description | The neural mechanisms underlying the spontaneous, stimulus-independent emergence of intentions and decisions to act are poorly understood. Using a neurobiologically realistic model of frontal and temporal areas of the brain, we simulated the learning of perception–action circuits for speech and hand-related actions and subsequently observed their spontaneous behaviour. Noise-driven accumulation of reverberant activity in these circuits leads to their spontaneous ignition and partial-to-full activation, which we interpret, respectively, as model correlates of action intention emergence and action decision-and-execution. Importantly, activity emerged first in higher-association prefrontal and temporal cortices, subsequently spreading to secondary and finally primary sensorimotor model-areas, hence reproducing the dynamics of cortical correlates of voluntary action revealed by readiness-potential and verb-generation experiments. This model for the first time explains the cortical origins and topography of endogenous action decisions, and the natural emergence of functional specialisation in the cortex, as mechanistic consequences of neurobiological principles, anatomical structure and sensorimotor experience. |
format | Online Article Text |
id | pubmed-3888926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-38889262014-01-13 Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas Garagnani, Max Pulvermüller, Friedemann Brain Lang Article The neural mechanisms underlying the spontaneous, stimulus-independent emergence of intentions and decisions to act are poorly understood. Using a neurobiologically realistic model of frontal and temporal areas of the brain, we simulated the learning of perception–action circuits for speech and hand-related actions and subsequently observed their spontaneous behaviour. Noise-driven accumulation of reverberant activity in these circuits leads to their spontaneous ignition and partial-to-full activation, which we interpret, respectively, as model correlates of action intention emergence and action decision-and-execution. Importantly, activity emerged first in higher-association prefrontal and temporal cortices, subsequently spreading to secondary and finally primary sensorimotor model-areas, hence reproducing the dynamics of cortical correlates of voluntary action revealed by readiness-potential and verb-generation experiments. This model for the first time explains the cortical origins and topography of endogenous action decisions, and the natural emergence of functional specialisation in the cortex, as mechanistic consequences of neurobiological principles, anatomical structure and sensorimotor experience. Elsevier 2013-10 /pmc/articles/PMC3888926/ /pubmed/23489583 http://dx.doi.org/10.1016/j.bandl.2013.02.001 Text en © 2013 Elsevier Inc. https://creativecommons.org/licenses/by/3.0/This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Garagnani, Max Pulvermüller, Friedemann Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title | Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title_full | Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title_fullStr | Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title_full_unstemmed | Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title_short | Neuronal correlates of decisions to speak and act: Spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
title_sort | neuronal correlates of decisions to speak and act: spontaneous emergence and dynamic topographies in a computational model of frontal and temporal areas |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888926/ https://www.ncbi.nlm.nih.gov/pubmed/23489583 http://dx.doi.org/10.1016/j.bandl.2013.02.001 |
work_keys_str_mv | AT garagnanimax neuronalcorrelatesofdecisionstospeakandactspontaneousemergenceanddynamictopographiesinacomputationalmodeloffrontalandtemporalareas AT pulvermullerfriedemann neuronalcorrelatesofdecisionstospeakandactspontaneousemergenceanddynamictopographiesinacomputationalmodeloffrontalandtemporalareas |