Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

Disruption to axonal transport is an early pathological feature in Alzheimer's disease. The amyloid precursor protein (APP) is a key axonal transport cargo in Alzheimer's disease since perturbation of its transport increases APP processing and production of amyloid-β peptide (Aβ) that is d...

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Detalles Bibliográficos
Autores principales: Vagnoni, Alessio, Glennon, Elizabeth B.C., Perkinton, Michael S., Gray, Emma H., Noble, Wendy, Miller, Christopher C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889811/
https://www.ncbi.nlm.nih.gov/pubmed/23825109
http://dx.doi.org/10.1093/hmg/ddt313

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