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Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
The severe acute respiratory syndrome (SARS) pandemic revealed that zoonotic transmission of animal coronaviruses (CoV) to humans poses a significant threat to public health and warrants surveillance and the development of countermeasures. The activity of host cell proteases, which cleave and activa...
Autores principales: | Simmons, Graham, Zmora, Pawel, Gierer, Stefanie, Heurich, Adeline, Pöhlmann, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889862/ https://www.ncbi.nlm.nih.gov/pubmed/24121034 http://dx.doi.org/10.1016/j.antiviral.2013.09.028 |
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