Hodgkin lymphoma transformation of chronic lymphocytic leukemia: cases report and discussion

B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common form of leukemia affecting adults in Europe and North America. Large B-cell lymphoma known as Richter’s syndrome (RS) may develop approximately in 3–15 % patients. Furthermore, other hematological malignancie...

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Detalles Bibliográficos
Autores principales: Kaźmierczak, Maciej, Kroll-Balcerzak, Renata, Balcerzak, Andrzej, Czechowska, Elżbieta, Gil, Lidia, Sawiński, Krzysztof, Szczepaniak, Andrzej, Komarnicki, Mieczysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890034/
https://www.ncbi.nlm.nih.gov/pubmed/24338339
http://dx.doi.org/10.1007/s12032-013-0800-8
Descripción
Sumario:B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is the most common form of leukemia affecting adults in Europe and North America. Large B-cell lymphoma known as Richter’s syndrome (RS) may develop approximately in 3–15 % patients. Furthermore, other hematological malignancies may also occur as RS variants, among them—Hodgkin lymphoma (HL). CLL/SLL transformation into HL is observed in about 0.5 % of patients, and till now, fewer than 100 cases have been reported in the medical literature. We present two cases of HL transformation of CLL/SLL and review the previously published literature.

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