DNA repair mechanisms and Toxoplasma gondii infection

Lately, we can observe significant progress in understanding mechanism of DNA repair owing to fast methods of DNA sequence analysis from different organisms the revealing of structure and function of DNA repair proteins in prokaryota and eukaryota. The protozoan parasites survival depends on DNA rep...

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Detalles Bibliográficos
Autores principales: Smolarz, Beata, Wilczyński, Jan, Nowakowska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890036/
https://www.ncbi.nlm.nih.gov/pubmed/24337694
http://dx.doi.org/10.1007/s00203-013-0944-0
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author Smolarz, Beata
Wilczyński, Jan
Nowakowska, Dorota
author_facet Smolarz, Beata
Wilczyński, Jan
Nowakowska, Dorota
author_sort Smolarz, Beata
collection PubMed
description Lately, we can observe significant progress in understanding mechanism of DNA repair owing to fast methods of DNA sequence analysis from different organisms the revealing of structure and function of DNA repair proteins in prokaryota and eukaryota. The protozoan parasites survival depends on DNA repair systems. Better understanding of DNA repair systems can help in new antipathogen drug development. This review is aimed at updating our current knowledge of the various repair pathways by providing an overview of DNA repair genes regarding Toxoplasma gondii infections and the corresponding proteins, participating either directly in DNA repair, or in checkpoint control and signaling of DNA damage.
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spelling pubmed-38900362014-01-28 DNA repair mechanisms and Toxoplasma gondii infection Smolarz, Beata Wilczyński, Jan Nowakowska, Dorota Arch Microbiol Mini-Review Lately, we can observe significant progress in understanding mechanism of DNA repair owing to fast methods of DNA sequence analysis from different organisms the revealing of structure and function of DNA repair proteins in prokaryota and eukaryota. The protozoan parasites survival depends on DNA repair systems. Better understanding of DNA repair systems can help in new antipathogen drug development. This review is aimed at updating our current knowledge of the various repair pathways by providing an overview of DNA repair genes regarding Toxoplasma gondii infections and the corresponding proteins, participating either directly in DNA repair, or in checkpoint control and signaling of DNA damage. Springer Berlin Heidelberg 2013-12-14 2014 /pmc/articles/PMC3890036/ /pubmed/24337694 http://dx.doi.org/10.1007/s00203-013-0944-0 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Mini-Review
Smolarz, Beata
Wilczyński, Jan
Nowakowska, Dorota
DNA repair mechanisms and Toxoplasma gondii infection
title DNA repair mechanisms and Toxoplasma gondii infection
title_full DNA repair mechanisms and Toxoplasma gondii infection
title_fullStr DNA repair mechanisms and Toxoplasma gondii infection
title_full_unstemmed DNA repair mechanisms and Toxoplasma gondii infection
title_short DNA repair mechanisms and Toxoplasma gondii infection
title_sort dna repair mechanisms and toxoplasma gondii infection
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890036/
https://www.ncbi.nlm.nih.gov/pubmed/24337694
http://dx.doi.org/10.1007/s00203-013-0944-0
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