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Silencing of CHD5 Gene by Promoter Methylation in Leukemia

Chromodomain helicase DNA binding protein 5 (CHD5) was previously proposed to function as a potent tumor suppressor by acting as a master regulator of a tumor-suppressive network. CHD5 is down-regulated in several cancers, including leukemia and is responsible for tumor generation and progression. H...

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Detalles Bibliográficos
Autores principales: Zhao, Rui, Meng, Fanyi, Wang, Nisha, Ma, Wenli, Yan, Qitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890315/
https://www.ncbi.nlm.nih.gov/pubmed/24454811
http://dx.doi.org/10.1371/journal.pone.0085172

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