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Silencing of CHD5 Gene by Promoter Methylation in Leukemia
Chromodomain helicase DNA binding protein 5 (CHD5) was previously proposed to function as a potent tumor suppressor by acting as a master regulator of a tumor-suppressive network. CHD5 is down-regulated in several cancers, including leukemia and is responsible for tumor generation and progression. H...
Autores principales: | Zhao, Rui, Meng, Fanyi, Wang, Nisha, Ma, Wenli, Yan, Qitao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890315/ https://www.ncbi.nlm.nih.gov/pubmed/24454811 http://dx.doi.org/10.1371/journal.pone.0085172 |
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