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Efficient Gene Delivery to Pig Airway Epithelia and Submucosal Glands Using Helper-Dependent Adenoviral Vectors

Airway gene delivery is a promising strategy to treat patients with life-threatening lung diseases such as cystic fibrosis (CF). However, this strategy has to be evaluated in large animal preclinical studies in order to translate it to human applications. Because of anatomic and physiological simila...

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Detalles Bibliográficos
Autores principales: Cao, Huibi, Machuca, Tiago N, Yeung, Jonathan C, Wu, Jing, Du, Kai, Duan, Cathleen, Hashimoto, Kohei, Linacre, Virginia, Coates, Allan L, Leung, Kitty, Wang, Jian, Yeger, Herman, Cutz, Ernest, Liu, Mingyao, Keshavjee, Shaf, Hu, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890457/
https://www.ncbi.nlm.nih.gov/pubmed/24104599
http://dx.doi.org/10.1038/mtna.2013.55

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