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RNA-Seq optimization with eQTL gold standards

BACKGROUND: RNA-Sequencing (RNA-Seq) experiments have been optimized for library preparation, mapping, and gene expression estimation. These methods, however, have revealed weaknesses in the next stages of analysis of differential expression, with results sensitive to systematic sample stratificatio...

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Detalles Bibliográficos
Autores principales: Ellis, Shannon E, Gupta, Simone, Ashar, Foram N, Bader, Joel S, West, Andrew B, Arking, Dan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890578/
https://www.ncbi.nlm.nih.gov/pubmed/24341889
http://dx.doi.org/10.1186/1471-2164-14-892