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Mitogen activated protein kinase kinase kinase 3 (MAP3K3/MEKK3) overexpression is an early event in esophageal tumorigenesis and is a predictor of poor disease prognosis

BACKGROUND: Mitogen-activated protein kinase kinase kinase3 (MAP3K3/MEKK3) was identified to be differentially expressed in esophageal squamous cell carcinoma (ESCC) using cDNA microarrays by our laboratory. Here in we determined the clinical significance of MEKK3 in ESCC. METHODS: Immunohistochemic...

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Detalles Bibliográficos
Autores principales: Hasan, Raghibul, Sharma, Rinu, Saraya, Anoop, Chattopadhyay, Tushar K, DattaGupta, Siddartha, Walfish, Paul G, Chauhan, Shyam S, Ralhan, Ranju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890584/
https://www.ncbi.nlm.nih.gov/pubmed/24383423
http://dx.doi.org/10.1186/1471-2407-14-2