Cargando…

Biosynthesis of the active compounds of Isatis indigotica based on transcriptome sequencing and metabolites profiling

BACKGROUD: Isatis indigotica is a widely used herb for the clinical treatment of colds, fever, and influenza in Traditional Chinese Medicine (TCM). Various structural classes of compounds have been identified as effective ingredients. However, little is known at genetics level about these active met...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Junfeng, Dong, Xin, Li, Qing, Zhou, Xun, Gao, Shouhong, Chen, Ruibing, Sun, Lianna, Zhang, Lei, Chen, Wansheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890716/ https://www.ncbi.nlm.nih.gov/pubmed/24308360 http://dx.doi.org/10.1186/1471-2164-14-857

Ejemplares similares

Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures
por: Chen, Ruibing, et al.
Publicado: (2015)

Dynamic metabolic and transcriptomic profiling of methyl jasmonate‐treated hairy roots reveals synthetic characters and regulators of lignan biosynthesis in Isatis indigotica Fort
por: Zhang, Lei, et al.
Publicado: (2016)

The dirigent multigene family in Isatis indigotica: gene discovery and differential transcript abundance
por: Li, Qing, et al.
Publicado: (2014)

Isatis indigotica: from (ethno) botany, biochemistry to synthetic biology
por: Feng, Jingxian, et al.
Publicado: (2021)

IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica
por: Xiao, Ying, et al.
Publicado: (2020)

AP2/ERF Transcription Factor, Ii049, Positively Regulates Lignan Biosynthesis in Isatis indigotica through Activating Salicylic Acid Signaling and Lignan/Lignin Pathway Genes
por: Ma, Ruifang, et al.
Publicado: (2017)

Tandem UGT71B5s Catalyze Lignan Glycosylation in Isatis indigotica With Substrates Promiscuity
por: Chen, Xiao, et al.
Publicado: (2021)

High-Throughput Sequencing and De Novo Assembly of the Isatis indigotica Transcriptome
por: Tang, Xiaoqing, et al.
Publicado: (2014)

Alkaloid Enantiomers from the Roots of Isatis indigotica
por: Zhang, Dongdong, et al.
Publicado: (2019)

Identification and investigation of a novel NADP(+)-dependent secoisolariciresinol dehydrogenase from Isatis indigotica
por: Shi, Xiaoyi, et al.
Publicado: (2022)

Computational Workflow to Study the Diversity of Secondary Metabolites in Fourteen Different Isatis Species
por: Huang, Doudou, et al.
Publicado: (2022)

Sulfur-enriched alkaloids from the root of Isatis indigotica
por: Guo, Qinglan, et al.
Publicado: (2018)

Three pairs of alkaloid enantiomers from the root of Isatis indigotica
por: Liu, Yufeng, et al.
Publicado: (2016)

Functional Characterization of UDP-Glycosyltransferases Involved in Anti-viral Lignan Glycosides Biosynthesis in Isatis indigotica
por: Tan, Yuping, et al.
Publicado: (2022)

Classification of Isatis indigotica Fortune and Isatis tinctoria Linnaeus via comparative analysis of chloroplast genomes
por: Su, Yong, et al.
Publicado: (2023)

Insights into glucosinolate accumulation and metabolic pathways in Isatis indigotica Fort.
por: Zhang, Tianyi, et al.
Publicado: (2022)

Identification of the bZIP gene family and regulation of metabolites under salt stress in isatis indigotica
por: Jiang, Ming, et al.
Publicado: (2022)

The complete chloroplast genome sequence of the medicinal and economic plant woad Isatis indigotica (Brassicaceae)
por: Yang, Shu, et al.
Publicado: (2017)

A Network Pharmacology-Based Investigation to the Pharmacodynamic Material Basis and Mechanisms of the Anti-Inflammatory and Anti-Viral Effect of Isatis indigotica
por: Deng, Jiuling, et al.
Publicado: (2021)

Identification of key gene networks controlling vernalization development characteristics of Isatis indigotica by full-length transcriptomes and gene expression profiles
por: Wang, Pan, et al.
Publicado: (2021)

The cytotoxicity to leukemia cells and antiviral effects of Isatis indigotica extracts on pseudorabies virus
por: Hsuan, Shih-Ling, et al.
Publicado: (2009)

Isatis indigotica root polysaccharides as adjuvants for an inactivated rabies virus vaccine
por: Zhang, Weijiao, et al.
Publicado: (2016)

Identification and characterization of two Isatis indigotica O-methyltransferases methylating C-glycosylflavonoids
por: Tan, Yuping, et al.
Publicado: (2022)

Photosynthetic Physiological Response of Radix Isatidis (Isatis indigotica Fort.) Seedlings to Nicosulfuron
por: Yuan, Xiangyang, et al.
Publicado: (2014)

Effects of water and nitrogen coupling on the photosynthetic characteristics, yield, and quality of Isatis indigotica
por: Wang, Yucai, et al.
Publicado: (2021)

The phenylalanine ammonia-lyase gene family in Isatis indigotica Fort.: molecular cloning, characterization, and expression analysis
por: MA, Rui-Fang, et al.
Publicado: (2016)

Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds
por: Lin, Cheng-Wen, et al.
Publicado: (2005)

Transcriptomic Analysis Reveals Differential Gene Expressions for Cell Growth and Functional Secondary Metabolites in Induced Autotetraploid of Chinese Woad (Isatis indigotica Fort.)
por: Zhou, Yingying, et al.
Publicado: (2015)

A chromosome-scale genome assembly of Isatis indigotica, an important medicinal plant used in traditional Chinese medicine: An Isatis genome
por: Kang, Minghui, et al.
Publicado: (2020)

Indole alkaloid sulfonic acids from an aqueous extract of Isatis indigotica roots and their antiviral activity
por: Meng, Lingjie, et al.
Publicado: (2017)

Physiological and biochemical responses of Isatis indigotica to deficit irrigation in a cold and arid environment
por: Zhou, Chenli, et al.
Publicado: (2023)

Untargeted liquid chromatography coupled with mass spectrometry reveals metabolic changes in nitrogen-deficient Isatis indigotica Fortune
por: Cao, Yi-Wen, et al.
Publicado: (2019)

Antiviral Activity of Isatis indigotica Extract and Its Derived Indirubin against Japanese Encephalitis Virus
por: Chang, Shu-Jen, et al.
Publicado: (2012)

Selection and Validation of Appropriate Reference Genes for qRT-PCR Analysis in Isatis indigotica Fort.
por: Li, Tao, et al.
Publicado: (2017)

Indole alkaloid glycosides with a 1′-(phenyl)ethyl unit from Isatis indigotica leaves
por: Guo, Qinglan, et al.
Publicado: (2020)

Polysaccharide Nanoparticles from Isatis indigotica Fort. Root Decoction: Diversity, Cytotoxicity, and Antiviral Activity
por: Gao, Guanzhen, et al.
Publicado: (2021)

SEPALLATA-like genes of Isatis indigotica can affect the architecture of the inflorescences and the development of the floral organs
por: Ma, Yan-Qin, et al.
Publicado: (2022)

Effects of Fully Open-Air [CO(2)] Elevation on Leaf Photosynthesis and Ultrastructure of Isatis indigotica Fort
por: Hao, Xingyu, et al.
Publicado: (2013)

Selection of reference genes for the quantitative real-time PCR normalization of gene expression in Isatis indigotica fortune
por: Qu, Renjun, et al.
Publicado: (2019)

Boiling-induced nanoparticles and their constitutive proteins from Isatis indigotica Fort. root decoction: Purification and identification
por: Zhou, Jianwu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jtgesamn2qq554v0r19rl0oan7