Cargando…

Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock

This is a report on a case of severe skin necrosis in a vasodilatory septic shock patient after the infusion of low-dose vasopressin through a central venous catheter. An 84-year-old male was hospitalized for edema on both legs at Asan Medical Center, Seoul, Korea. On hospital day 8, the patient beg...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun Hee, Lee, Sae Hwan, Byun, Seung Woon, Kang, Ho Suk, Koo, Dong Hoe, Park, Hyun-Gu, Hong, Sang Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891039/
https://www.ncbi.nlm.nih.gov/pubmed/17249516
http://dx.doi.org/10.3904/kjim.2006.21.4.287
_version_ 1782299336279851008
author Kim, Eun Hee
Lee, Sae Hwan
Byun, Seung Woon
Kang, Ho Suk
Koo, Dong Hoe
Park, Hyun-Gu
Hong, Sang Bum
author_facet Kim, Eun Hee
Lee, Sae Hwan
Byun, Seung Woon
Kang, Ho Suk
Koo, Dong Hoe
Park, Hyun-Gu
Hong, Sang Bum
author_sort Kim, Eun Hee
collection PubMed
description This is a report on a case of severe skin necrosis in a vasodilatory septic shock patient after the infusion of low-dose vasopressin through a central venous catheter. An 84-year-old male was hospitalized for edema on both legs at Asan Medical Center, Seoul, Korea. On hospital day 8, the patient began to complain of dyspnea and he subsequently developed severe septic shock caused by E. coli. After being transferred to the medical intensive care unit, his hypotension, which was refractory to norepinephrine, was controlled by an infusion of low-dose vasopressin (0.02 unit/min) through a central venous catheter into the right subclavian vein. After the infusion of low-dose vasopressin, severe skin necrosis with bullous changes developed, necessitating discontinuation of the low-dose vasopressin infusion. The patient expired from refractory septic shock. Although low-dose vasopressin can control hypotension in septic shock patients, low-dose vasopressin must be used with caution because ischemic complications such as skin necrosis can develop even with administration through a central venous catheter.
format Online
Article
Text
id pubmed-3891039
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher The Korean Association of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-38910392014-01-16 Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock Kim, Eun Hee Lee, Sae Hwan Byun, Seung Woon Kang, Ho Suk Koo, Dong Hoe Park, Hyun-Gu Hong, Sang Bum Korean J Intern Med Case Report This is a report on a case of severe skin necrosis in a vasodilatory septic shock patient after the infusion of low-dose vasopressin through a central venous catheter. An 84-year-old male was hospitalized for edema on both legs at Asan Medical Center, Seoul, Korea. On hospital day 8, the patient began to complain of dyspnea and he subsequently developed severe septic shock caused by E. coli. After being transferred to the medical intensive care unit, his hypotension, which was refractory to norepinephrine, was controlled by an infusion of low-dose vasopressin (0.02 unit/min) through a central venous catheter into the right subclavian vein. After the infusion of low-dose vasopressin, severe skin necrosis with bullous changes developed, necessitating discontinuation of the low-dose vasopressin infusion. The patient expired from refractory septic shock. Although low-dose vasopressin can control hypotension in septic shock patients, low-dose vasopressin must be used with caution because ischemic complications such as skin necrosis can develop even with administration through a central venous catheter. The Korean Association of Internal Medicine 2006-12 2006-12-31 /pmc/articles/PMC3891039/ /pubmed/17249516 http://dx.doi.org/10.3904/kjim.2006.21.4.287 Text en Copyright © 2006 The Korean Association of Internal Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Eun Hee
Lee, Sae Hwan
Byun, Seung Woon
Kang, Ho Suk
Koo, Dong Hoe
Park, Hyun-Gu
Hong, Sang Bum
Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title_full Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title_fullStr Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title_full_unstemmed Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title_short Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
title_sort skin necrosis after a low-dose vasopressin infusion through a central venous catheter for treating septic shock
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891039/
https://www.ncbi.nlm.nih.gov/pubmed/17249516
http://dx.doi.org/10.3904/kjim.2006.21.4.287
work_keys_str_mv AT kimeunhee skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT leesaehwan skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT byunseungwoon skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT kanghosuk skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT koodonghoe skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT parkhyungu skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock
AT hongsangbum skinnecrosisafteralowdosevasopressininfusionthroughacentralvenouscatheterfortreatingsepticshock