Adult Onset Still's Disease as a Cause of Acute Severe Mitral and Aortic Regurgitation

Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly, and serositis. Pericarditis is the most common c...

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Detalles Bibliográficos
Autores principales: Lee, Jae Seung, Do, Il No, Kang, Deok Hyun, Joo, Seok Jung, Yoo, Bin, Moon, Hee Bom, Lee, Chang-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2005
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891165/
https://www.ncbi.nlm.nih.gov/pubmed/16295789
http://dx.doi.org/10.3904/kjim.2005.20.3.264
Descripción
Sumario:Adult onset Still's disease (AOSD) is an uncommon acute systemic inflammatory disease of unknown origin. The clinical features include high spiking fever, arthralgia or arthritis, transient maculopapular rash, lymphadenopathy, hepatosplenomegaly, and serositis. Pericarditis is the most common cardiac manifestation of AOSD and occurs in approximately 30% of cases. A simultaneous occurrence of rapidly progressive bi-valvular regurgitation associated with AOSD has not been previously described. We report a case of a 55-year old woman who underwent mitral valve replacement and Bentall's operation due to acute severe mitral and aortic regurgitation associated with AOSD.

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