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The Role of Intestinal Microbiota in Development of Irinotecan Toxicity and in Toxicity Reduction through Dietary Fibres in Rats

CPT-11 is a drug used as chemotherapy for colorectal cancer. CPT-11 causes toxic side-effects in patients. CPT-11 toxicity has been attributed to the activity of intestinal microbiota, however, intestinal microbiota may also have protective effects in CP!-11 chemotherapy. This study aimed to elucida...

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Detalles Bibliográficos
Autores principales:	Lin, Xiaoxi B., Farhangfar, Arazm, Valcheva, Rosica, Sawyer, Michael B., Dieleman, Levinus, Schieber, Andreas, Gänzle, Michael G., Baracos, Vickie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891650/ https://www.ncbi.nlm.nih.gov/pubmed/24454707 http://dx.doi.org/10.1371/journal.pone.0083644

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