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Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature

BACKGROUND: Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains a matter of debate and diagnostic criteria have not yet been defined. CASE PRESENTATION: The general status of a 74-year-ol...

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Autores principales: Ogawa, Yukari, Saraya, Takeshi, Koide, Takashi, Kikuchi, Ken, Ohkuma, Kosuke, Araki, Koji, Makino, Hiroshi, Yonetani, Shota, Takizawa, Hajime, Goto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892063/
https://www.ncbi.nlm.nih.gov/pubmed/24405901
http://dx.doi.org/10.1186/1756-0500-7-21
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author Ogawa, Yukari
Saraya, Takeshi
Koide, Takashi
Kikuchi, Ken
Ohkuma, Kosuke
Araki, Koji
Makino, Hiroshi
Yonetani, Shota
Takizawa, Hajime
Goto, Hajime
author_facet Ogawa, Yukari
Saraya, Takeshi
Koide, Takashi
Kikuchi, Ken
Ohkuma, Kosuke
Araki, Koji
Makino, Hiroshi
Yonetani, Shota
Takizawa, Hajime
Goto, Hajime
author_sort Ogawa, Yukari
collection PubMed
description BACKGROUND: Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains a matter of debate and diagnostic criteria have not yet been defined. CASE PRESENTATION: The general status of a 74-year-old Japanese man referred to our hospital (day 1) with severe community-acquired pneumococcal pneumonia gradually improved with antibiotic therapy. Thereafter, up to 4 L/day of acute watery diarrhea that started on day 19 was refractory to metronidazole but responded immediately to oral vancomycin. Gram staining stool samples was positive for abundant fecal leukocytes from which dominant methicillin-resistant Staphylococcus aureus (10(4) CFU/mL) were isolated, suggesting methicillin-resistant Staphylococcus aureus enterocolitis. High fever with methicillin-resistant Staphylococcus aureus bacteremia was evident at day 30, and suppurative right hip arthritis developed around day 71. All methicillin-resistant Staphylococcus aureus strains isolated from stools, blood and aspirated synovial fluid separated in the same manner on pulsed-field gel electrophoresis, as well as two other strains isolated from sputum, belonged to the same clone as sequence type (ST) 764 (complex clonal 5), and carried SCCmec type II. CONCLUSION: The clinical, microbiological and molecular biological findings of this patient indicated methicillin-resistant Staphylococcus aureus enterocolitis that led to septic methicillin-resistant Staphylococcus aureus arthritis.
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spelling pubmed-38920632014-01-15 Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature Ogawa, Yukari Saraya, Takeshi Koide, Takashi Kikuchi, Ken Ohkuma, Kosuke Araki, Koji Makino, Hiroshi Yonetani, Shota Takizawa, Hajime Goto, Hajime BMC Res Notes Case Report BACKGROUND: Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains a matter of debate and diagnostic criteria have not yet been defined. CASE PRESENTATION: The general status of a 74-year-old Japanese man referred to our hospital (day 1) with severe community-acquired pneumococcal pneumonia gradually improved with antibiotic therapy. Thereafter, up to 4 L/day of acute watery diarrhea that started on day 19 was refractory to metronidazole but responded immediately to oral vancomycin. Gram staining stool samples was positive for abundant fecal leukocytes from which dominant methicillin-resistant Staphylococcus aureus (10(4) CFU/mL) were isolated, suggesting methicillin-resistant Staphylococcus aureus enterocolitis. High fever with methicillin-resistant Staphylococcus aureus bacteremia was evident at day 30, and suppurative right hip arthritis developed around day 71. All methicillin-resistant Staphylococcus aureus strains isolated from stools, blood and aspirated synovial fluid separated in the same manner on pulsed-field gel electrophoresis, as well as two other strains isolated from sputum, belonged to the same clone as sequence type (ST) 764 (complex clonal 5), and carried SCCmec type II. CONCLUSION: The clinical, microbiological and molecular biological findings of this patient indicated methicillin-resistant Staphylococcus aureus enterocolitis that led to septic methicillin-resistant Staphylococcus aureus arthritis. BioMed Central 2014-01-09 /pmc/articles/PMC3892063/ /pubmed/24405901 http://dx.doi.org/10.1186/1756-0500-7-21 Text en Copyright © 2014 Ogawa et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Ogawa, Yukari
Saraya, Takeshi
Koide, Takashi
Kikuchi, Ken
Ohkuma, Kosuke
Araki, Koji
Makino, Hiroshi
Yonetani, Shota
Takizawa, Hajime
Goto, Hajime
Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title_full Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title_fullStr Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title_full_unstemmed Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title_short Methicillin-resistant Staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
title_sort methicillin-resistant staphylococcus aureus enterocolitis sequentially complicated with septic arthritis: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892063/
https://www.ncbi.nlm.nih.gov/pubmed/24405901
http://dx.doi.org/10.1186/1756-0500-7-21
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