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Differential inflammasome expression and IL-1β secretion in monocyte-derived dendritic cells differentiated with IL-4 or IFN-α
BACKGROUND: NLRP3-inflammasome activation was evaluated in monocyte-derived dendritic cells (DC) obtained through IL-4 (IL4-DC) or IFN-α (IFN-DC) protocols and pulsed with chemically inactivated HIV-1. Inflammasome’ genes expression and IL-1β secretion were compared in DC isolated from 15 healthy su...
Autores principales: | Pontillo, Alessandra, Santillo, Bruna T, Duarte, Alberto JS, Oshiro, Telma M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892092/ https://www.ncbi.nlm.nih.gov/pubmed/24373498 http://dx.doi.org/10.1186/1742-6405-10-35 |
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