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Functional coupling of chloride–proton exchanger ClC-5 to gastric H(+),K(+)-ATPase
It has been reported that chloride–proton exchanger ClC-5 and vacuolar-type H(+)-ATPase are essential for endosomal acidification in the renal proximal cells. Here, we found that ClC-5 is expressed in the gastric parietal cells which secrete actively hydrochloric acid at the luminal region of the gl...
Autores principales: | Takahashi, Yuji, Fujii, Takuto, Fujita, Kyosuke, Shimizu, Takahiro, Higuchi, Taiga, Tabuchi, Yoshiaki, Sakamoto, Hisato, Naito, Ichiro, Manabe, Koji, Uchida, Shinichi, Sasaki, Sei, Ikari, Akira, Tsukada, Kazuhiro, Sakai, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892156/ https://www.ncbi.nlm.nih.gov/pubmed/24429108 http://dx.doi.org/10.1242/bio.20136205 |
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