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IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis

Interleukin 4 (IL-4) was shown to be tumor-promoting in full carcinogenesis studies using 3-methylcholanthrene (MCA). Because heretofore the role of IL-4 in DMBA/TPA (9,10-dimethyl-1,2-benz-anthracene/12-O-tetradecanoylphorbol-13-acetate) two-stage carcinogenesis was not studied, we performed such e...

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Detalles Bibliográficos
Autores principales:	Rothe, Michael, Quarcoo, David, Chashchina, Anna A, Bozrova, Svetlana V, Qin, Zhihai, Nedospasov, Sergei A, Blankenstein, Thomas, Kammertoens, Thomas, Drutskaya, Marina S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892386/ https://www.ncbi.nlm.nih.gov/pubmed/24403255 http://dx.doi.org/10.1002/cam4.145

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