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Specificity Residues Determine Binding Affinity for Two-Component Signal Transduction Systems

Two-component systems (TCS) comprise histidine kinases and their cognate response regulators and allow bacteria to sense and respond to a wide variety of signals. Histidine kinases (HKs) phosphorylate and dephosphorylate their cognate response regulators (RRs) in response to stimuli. In general, the...

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Detalles Bibliográficos
Autores principales: Willett, Jonathan W., Tiwari, Nitija, Müller, Susanne, Hummels, Katherine R., Houtman, Jon C. D., Fuentes, Ernesto J., Kirby, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892784/
https://www.ncbi.nlm.nih.gov/pubmed/24194534
http://dx.doi.org/10.1128/mBio.00420-13