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Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor
Epithelial to mesenchymal transition (EMT) is considered an important mechanism in tumor resistance to drug treatments; however, in vivo observation of this process has been limited. In this study we demonstrated an immediate and widespread EMT involving all surviving tumor cells following treatment...
Autores principales: | Fifis, Theodora, Nguyen, Linh, Malcontenti-Wilson, Cathy, Chan, Lie Sam, Nunes Costa, Patricia Luiza, Daruwalla, Jurstine, Nikfarjam, Mehrdad, Muralidharan, Vijayaragavan, Waltham, Mark, Thompson, Erik W, Christophi, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892792/ https://www.ncbi.nlm.nih.gov/pubmed/24403226 http://dx.doi.org/10.1002/cam4.109 |
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