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Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor

Epithelial to mesenchymal transition (EMT) is considered an important mechanism in tumor resistance to drug treatments; however, in vivo observation of this process has been limited. In this study we demonstrated an immediate and widespread EMT involving all surviving tumor cells following treatment...

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Detalles Bibliográficos
Autores principales: Fifis, Theodora, Nguyen, Linh, Malcontenti-Wilson, Cathy, Chan, Lie Sam, Nunes Costa, Patricia Luiza, Daruwalla, Jurstine, Nikfarjam, Mehrdad, Muralidharan, Vijayaragavan, Waltham, Mark, Thompson, Erik W, Christophi, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892792/
https://www.ncbi.nlm.nih.gov/pubmed/24403226
http://dx.doi.org/10.1002/cam4.109

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