Contrasting Effects of Systemic Monocyte/Macrophage and CD4(+) T Cell Depletion in a Reversible Ureteral Obstruction Mouse Model of Chronic Kidney Disease

Using a reversible UUO model (rUUO), we have demonstrated that C57BL/6 mice are susceptible to development of CKD after obstruction-mediated kidney injury while BALB/c mice are resistant. We hypothesized that selective systemic depletion of subpopulations of inflammatory cells during injury or repai...

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Detalles Bibliográficos
Autores principales: Chaves, Lee D., Mathew, Liby, Shakaib, Mohammed, Chang, Anthony, Quigg, Richard J., Puri, Tipu S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892942/
https://www.ncbi.nlm.nih.gov/pubmed/24489579
http://dx.doi.org/10.1155/2013/836989

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